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KMID : 0614619930250061349
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Korean Journal of Gastroenterology
1993 Volume.25 No. 6 p.1349 ~ p.1355
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A Case of Gardner's Syndrome Associated with Adenomata of Gallbladder
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임현이
신석균/김남규/유효민/김희성/김원호/김태승/낙찬일
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Abstract
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Gardner's syndrome is a rare hereditary disorder transmitted by autosomal dominant inheritance and charactrized by multiple adenomatous polyps throughout large intestine associated with multiple osteomas, epidermal cysts, fibromas, etc.
Extracolic
tumors such as periampullary carcinoma, patillary carcinoma of the thyroid gland, adrenal adenoma/carcinoma and tumors of the CNS have been reported to be associated with Gardner's syndrome. The authors report a case of Gardner's syndrome in a
53-year-old male who presented colorectal polyposis with osteoma of the frontal bone, schwannoma of neck and multiple adenomas of the galbladder. A review of literature with emphasis on the association of adenomata of the gallbladder was made.
The
colorectum was carpeted by multiple sessile and pedunculated polyps with microscopic foci of adenocarcinoma confined to the submucosa. The gallbladder was stuffed with multiple polyps, which were histologically adenomas with varying degrees of
atypical
change from mild dysplasia to carcinoma in situ.
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KEYWORD
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